DESCRIPTION:
Job listing on Nature Careers: https://www.nature.com/naturecareers/job?id=682759
A funded post-doctoral position is available in the laboratory of Nathaniel Landau in the Department of Microbiology at the NYU School of Medicine. Research focus on virus:host interactions and the immune response to HIV infection. Available projects are: (i) Identification of novel lentiviral restriction factors. (ii) The development of a therapeutic DC vaccine for HIV. (iii) The role of Vpr and Vpx lentiviral accessory proteins in counteracting host restriction factors in overcoming proviral transcriptional silencing in myeloid and T cells. NYU School of Medicine, in mid-town Manhattan, in the Alexandria Center for Life Sciences, offers a rich scientific and intellectual environment for collaborative projects and cutting edge core facilities. Subsidized housing is available and benefits are included. The Alexandria Center for Life Sciences provides first-rate facilities and opportunities for interaction with industry partners.
PUBLICATIONS:
Jáuregui P and N.R. Landau. (2018). DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1. Sci Rep. 8:4153. PMID: 29515139.
Hofmann, H., Vanwalscappel, B., Bloch, N., N.R. Landau. (2016). TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes. Retrovirology. 13(1)83. PMID 27905985.
Norton TD, Miller EA, Bhardwaj N, Landau NR. (2015) Vpx-containing dendritic cell vaccine induces CTLs and reactivates latent HIV-1 in vitro. Gene Therapy. 22(3):11-20. PMID: 25567537.
Lahouassa, H., Daddacha, W., Hofmann, H., Ayinde, D., Logue, EC, Dragin, L., Bloch, N., Maudet, C., Bertrand, M., Gramberg, T., Pancino, G., Priet, S., Canard, B., Laguette, N., Benkirane, M., Transy, C., Landau, NR., Kim, B. & Margottin-Goguet, F. (2013). SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat Immunol., 14(8):877. PMID: 23867943.
REQUIREMENTS:
Candidate must hold a Ph.D. and have a background in molecular biology with previous publications. Candidate must be motivated and interested to join an interactive research group.
FUNDING AND SALARY:
Funds are provided through NIH research grants and departmental training grants. Salary is commensurate with suggested NIH postdoctoral salary guidelines.
Qualified applicants should send C.V., brief statement of research interests and contact information for three references to Nathaniel.landau@med.nyu.edu.
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